TREATMENT-AND-PROPHYLACTIC PREPARATION "GEKSIKON" WITH ANTIBACTERIAL AND ANTISEPTIC ACTION Russian patent published in 2001 - IPC

Abstract RU 2166314 C2

FIELD: medicine, particularly, pharmaceutical production. SUBSTANCE: invention deals with preparing a new medicinal agent in the form of suppository on base of bigluconate chlorhexine. The agent may have a wide application for treatment of urogenital pathology of women and prophylaxis of venereal diseases, such as syphilis, gonorrhea and trichomonosis. The new treatment-and-prophylactic preparation "Geksikon" on base of bigluconate chorhexine is made in the form of suppository and additionally contains a bade at the following ratio of components, g per one suppository: bigluconate chlorhexine, 0.014-0.018; base, the balance. As a base it contains hydrophilic one, preferably, polyethyleneoxide base. Preferably used in polyethyleneoxide base is polyethyleneoxide with maximum molecular moisture- absorbing capacity 1500 in the amount of 92-98% and polyzhethyleneoxide with maximum molecular moisture-absorbing capacity 400 in the amount of 2-8%. Hydrophilic base is used in the amount sufficient for preparation of a suppository with mass of 2.90-3.25 g. Bigluconate chlorhexine is preferably used as 20-% aqueous solution. The proposed preparation is well endured by patients, nontoxic and does not cause allergy and side effects. EFFECT: higher antiseptic and antibacterial action; higher efficiency for treatment and prophylaxis of venereal diseases. 4 cl, 1 tbl, 4 ex

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RU 2 166 314 C2

Authors

Ehl'Natanova M.I.

Krupennikova N.A.

Shmeleva V.N.

Surkova L.N.

Usoeva L.A.

Shamanina E.M.

Dates

2001-05-10Published

1999-07-06Filed