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2 171 115

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IPC

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Application

98102952/14, 1998-02-19

(24)

Start date

1998-02-19

(22)

Actual filing date

1998-02-19

(45)

Published

2001-07-27

(72)

Inventor

Lishmanov Ju.B.Maslov L.N.Lasukova T.V.Krylatov A.V.

(73)

Holder

Nauchno-Issledovatel'Skij Institut Kardiologii Tomskogo Nauchnogo Tsentra So Ramn

ANTIARRHYTHMIC AGENT Russian patent published in 2001 - IPC

Abstract RU 2171115 C2

FIELD: medicine, cardiology, chemistry of peptides. SUBSTANCE: invention proposes the novel antiarrhythmic agent of the I-st class that is heptadecapeptide of the following amino acid composition: Phe-Gly-Gly-Phe-Thr- -Gly-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Ser-Ala-Arg-Lys-Leu-Ala-Asp- -Gln. This peptide is known as nocipentin. Efficiency of the proposed preparation is 10-fold more as compared with that of the known antiarrhythmic agent mexitil of the I-st class as tested in model of aconotine arrhythmias. EFFECT: enhanced effectiveness of agent. 2 tbl

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RU 2 171 115 C2

Authors

Lishmanov Ju.B.

Maslov L.N.

Lasukova T.V.

Krylatov A.V.

Dates

2001-07-27—Published

1998-02-19—Filed

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