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2 260 442

(13)

(51)

IPC

(21) (22)

Application

2004103119/15, 2004-02-03

(24)

Start date

2004-02-03

(22)

Actual filing date

2004-02-03

(45)

Published

2005-09-20

(72)

Inventor

Maslov L.N.Lishmanov Ju.B.Krylatov A.V.Lishmanov A.Ju.Budankova E.V.

(73)

Holder

Gu Nauchno-Issledovatel'Skij Institut Kardiologii Tomskogo Nauchnogo Tsentra So Ramn

ANTI-ARRHYTHMIC AGENT Russian patent published in 2005 - IPC

Abstract RU 2260442 C1

FIELD: medicine, chemistry of peptides.

SUBSTANCE: invention proposes a new anti-arrhythmic agent that represents a peptide ligand of opioid receptors deltorphine D - compound of the formula (I): Tyr-D-Leu-Phe-Ala-Asp-Val-Ala-Ser-Thr-Ile-Gly-Asp-Phe-His-Ser-Ile-NH₂ (I). The effect of this agent is associated with stimulation of opioid receptors and results to reducing frequency in arising multiple ventricular extrasystoles and episodes of ventricular tachycardia.

EFFECT: valuable medicinal properties of agent.

1 tbl, 1 ex

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RU 2 260 442 C1

Authors

Maslov L.N.

Lishmanov Ju.B.

Krylatov A.V.

Lishmanov A.Ju.

Budankova E.V.

Dates

2005-09-20—Published

2004-02-03—Filed