FIELD: medicine, immunology, pharmacy. SUBSTANCE: invention relates to monoclonal antibody Ab2 simulating internal image of antigen EGFR that is prepared from murine antibody mAb 425 and producing by cell line deposited at number ATCC HB 9629. Invention relates to also method of antibody preparing by immunization of animals with corresponding idiotypical antibody and pharmaceutical composition based on thereof. New prepared product is good candidate for idiotypical vaccine used for inhibition of tumor proliferation. EFFECT: new product indicated above, valuable antitumor properties. 6 cl, 15 dwg, 5 tbl, 15 ex
| Title |
Year |
Author |
Number |
| IMMUNOCONJUGATES, PREPARATION METHOD, AND PHARMACEUTICAL COMPOSITION |
1995 |
- Vol'Fgang Khel'Tser
- Ilka Fon Khoegen
- Vol'Fgang Shtrittmatter
- Zigfrid Mattsku
|
RU2157701C2 |
| IMMUNOCONJUGATE, A METHOD OF AN IMMUNOCONJUGATE PREPARING AND A PHARMACEUTICAL COMPOSITION |
1994 |
- Ilka Fon Khegen
- Uve Khofmann
- Karlotta-Sil'Vija Eggle
- Vol'Fgang Shtrittmatter
- Jorg Shtadl'Mjuller
- Zigfrid Mattsku
|
RU2129018C1 |
| MONOCLONAL ANTI-IDIOTYPIC ANTIBODY AB2, METHOD FOR ITS PREPARING, USAGE AGAINST DISEASES ACCOMPANYING WITH EXPRESSION OF LEWIS Y6 ANTIGEN AND FOR PURIFICATION OF ANTIBODY VARIANT BR 55-2, CURATIVE-PROPHYLACTIC COMPOSITION |
1993 |
- Ehkert Khel'Mut
- Jakshe Kherbert
- Janzek Ehvelin
- Lejbner Khans
- Shol'Ts Diter
|
RU2208642C2 |
| PHARMACEUTICAL COMPOSITIONS AIMED AT Erb-B1 RECEPTORS |
2003 |
- Krejsh Khans-Georg
- Shmidt Jurgen
|
RU2354402C2 |
| BISPECIFIC ANTIGEN MOLECULE FOR LYSIS OF TUMOR CELLS, METHOD FOR PREPARING F(AB')2 FRAGMENT OF BISPECIFIC ANTIGEN MOLECULE, MONOCLONAL ANTIBODY (VERSIONS), PHARMACEUTICAL PREPARATION, PHARMACEUTICAL KIT FOR LYSIS OF TUMOR CELLS (VERSIONS), METHOD OF LYSIS OF TUMOR CELLS EX VIVO IN AUTOGENOUS BONE MARROW TRANSPLANTATION |
1994 |
- Shtrittmatter Vol'Fgang
- Jeggle Karlota-Sil'Via
- Mojer Shtefan
- Burkkhart Shraven
- Vil'D Martin
|
RU2203319C2 |
| ANTI-EGFR SINGLE-CHAIN FV, CHIMERIC ANTI-EGFR ANTIBODY AND METHOD OF ITS PREPARING, PHARMACEUTICAL COMPOSITION FOR TREATMENT OF PATIENTS WITH TUMORS, AGENT FOR DIAGNOSIS OF LOCALIZATION AND ESTIMATION OF TUMOR GROWTH |
1995 |
- A. Kehtrin Kettleboru
- Mehri M. Bendig
- Kejt Kh. Ehnsell
- Detlef Gjussov
- Khaume Adan
- Fransesk Mitkhans
- Ehlizabet Rossel'
- Fransesk Blasko
- Khaume Piulats
|
RU2170257C2 |
| MONOCLONAL ANTIBODY RAISED AGAINST αV-INTEGRINS (VARIANTS), ITS PREPARING (VARIANTS) AND USING, HYBRIDOMA, POLYPEPTIDE, DNA |
1995 |
- Mitkhans Fransesk
- Piulats Khaume
- Rosel' Ehlizabet
- Adan Khaume
- Gudman Sajmon
- Khan Dajane
|
RU2205223C2 |
| COMBINED THERAPY USING INHIBITORS OF TYROSINE KINASE RECEPTORS AND INHIBITORS OF ANGIOGENESIS |
2001 |
- Gudman Sajmon
- Krejsh Khans-Georg
|
RU2292904C2 |
| MODIFIED ANTI-EGFR ANTIBODIES WITH REDUCED AMMONOGENICITY |
2002 |
- Karr Frehnsis Dzh.
- Karter Grehm
- Dzhons Tim
- Uill'Jams Stiven
- Khamil'Ton Anita
|
RU2297245C2 |
| HIGH-CONCENTRATION LIQUID ANTI-EGFR ANTIBODY COMPOSITIONS |
2005 |
- Mateus Zuzanne
- Maler Khanns-Kristian
|
RU2390353C2 |
