IMMUNOFYLLINE-SPECIFIC LIGANDS AS ANTIASTHMATIC AND IMMUNO-DEPRESSANT AGENTS AND METHOD OF THEIR SYNTHESIS, PHARMACEUTICALLY READY FORM, MEDICINAL AGENT AND METHOD OF ITS PREPARING Russian patent published in 2001 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes novel immunofylline- specific ligands of the general formula (I) where R₁ is residue of amino acid methyl ester taken among ε-NH₂- lysine, ε-lysine, phenylalanine; R₂ is hydrogen atom; R is butylhydroxycarbonyl, carboxybenzyl, residue of 4-piperidine carboxylic acid, 2-indoline carboxylic acid; R₄ is hydrogen atom; A is aromatic group; β-D is -CH = C-; X is O; Y is C. They show antiasthmatic and immunodepressant effect and can be used as the parent compounds for synthesis of medicinal agents. Invention describes also method of their synthesis, pharmaceutically ready form, medicinal agent and method of its preparing. EFFECT: new compounds indicated above, improved method of synthesis, valuable medicinal properties. 19 cl, 3 tbl, 13 ex