FIELD: pharmaceutical technology, pharmacy. SUBSTANCE: invention relates to a novel method that involves raw preparing, separate successive granulation of medicinal agent components by each component wetting with binding agent solution in combination with simultaneous drying up to preparing coating on granules. Granules are dried to the moisture value 0.1-2.2%, mixed and packaged. Agent is obtained in the form of granulated powder. For preparing agent the following components are used, g per package: acetylsalicylic acid or paracetamol, 0.18-0.58; ascorbic acid, 0.08-0.22; calcium gluconate, 0.08-0.22; dimedrol and/or rutin, 0.018-0.058; binding agents, 0.002- -8.982; aromatic substances, 0.002-1.00. Starch and/or polyvinylpyrrolidone, and/or glucose, and/or sucrose, and/or lactose, and/or gelatin are used as a binding agents. Method provides preparing an anti-inflammatory analgetic agent with stable quality for 1 year. EFFECT: improved method of preparing, increased stability of agent. 4 cl, 4 tbl, 4 ex
Authors
Dates
2001-09-20—Published
1998-01-28—Filed