FIELD: medicine, pharmacy. SUBSTANCE: invention relates to biodegradable implants prepared as a composition for controllable release of medicinal agents. Invention presents combinations of hydrophilic and hydrophobic forms in biodegradable implant of prolonged action designated for modulation of the release rate of each component. Compositions of therapeutically active agent and modulating agent provide the constant rate of release for a long time. EFFECT: improved properties of composition. 27 cl, 3 dwg, 6 ex
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