METHODS FOR TREATING PATHOLOGY OF EYE BY MEANS OF IMPLANT WITH DURABLE DELIVERY OF DRUG SUBJECTS Russian patent published in 2019 - IPC A61K31/573 A61K9/10 A61K47/56 A61P27/02 

Abstract RU 2690841 C1

FIELD: medicine.

SUBSTANCE: invention refers to a method for treating diabetic macular edema. Method comprises injecting a biodegradable implant into a vitreous body having readings thereon at a frequency from once every six months to once every nine months for at least three years, wherein the biodegradable implant comprises a continuous double-extruded rod containing dexamethasone homogeneously dispersed in the biodegradable polymer matrix; wherein the biodegradable polymer matrix consists of a mixture of poly (D,L-lactide-co-glycolide) (PLGA), having hydrophilic end groups, and poly (D,L-lactide-co-glycolide) (PLGA), having hydrophobic end groups.

EFFECT: method is therapeutically effective for treating diabetic macular edema and leads to the improvement of human visual acuity by 15 or more letters for at least three years.

7 cl, 7 dwg, 1 ex, 5 tbl

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RU 2 690 841 C1

Authors

Shia Dzhejn-Guo

Bagat Raul

Blanda Vendi M.

Nivagzhioli Terri

Pen Lin

Chou Devid

Veber Devid A.

Dates

2019-06-06Published

2014-11-14Filed