FIELD: microbiology, medicinal and biological industry. SUBSTANCE: after fermentation of mutant strain Micromonospora echinospora CGMCC 0197 the monocomponent gentamycin of type C1a is prepared which after purification is used for synthesis of antibiotic 1-N-ethylgentamycin C1a. Semisynthetic 1-N-ethylgentamycin C1a synthesized by indicated method is added to composition as an active component being this composition except for indicated antibiotic has pharmaceutically acceptable neutral carriers and shows the expressed antibacterial effect. Invention can be used in medicinal practice. EFFECT: improved method of synthesis and preparing. 11 dwg, 7 tbl
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Authors
Dates
2002-03-10—Published
1994-04-23—Filed