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Application

2000129622/13, 2000-11-28

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Start date

2000-11-28

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Actual filing date

2000-11-28

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Published

2002-11-10

(72)

Inventor

Lagutkin N.A.Smirnov V.N.Juzhuk T.Eh.Lunitsin A.V.Malogolovkina N.V.Bobrovskaja N.K.Balyshev V.M.

(73)

Holder

Vnii Veterinarnoj Virusologii I Mikrobiologii

STRAIN "LP" OF PARAMYXOVIRUS OF FIRST SEROTYPE FOR CONTROL OF IMMUNOGENIC ACTIVITY OF VACCINES AGAINST NEWCASTLE DISEASE Russian patent published in 2002 - IPC

Abstract RU 2192278 C2

FIELD: veterinary virology. SUBSTANCE: invention relates to poultry paramyxovirus strains. Strain is obtained by isolation of Newcastle disease virus isolate from poultry pathological material delivered from poultry plant. Strain "LP" is deposited in Collection of microorganism strains VNII of veterinary virology and microbiology RASCHN. Strain "LP" is used as control one in evaluation of immunogenic activity of vaccines against Newcastle disease shows higher infectious activity (7.0 lg 50/cm3, 9.5 lg ELD 50/cm3) with more expressed pathoanatomical alternations: hemorrhages in upper third of muscular stomach under cuticle, more distinct multiple hemorrhages on glandular stomach mucosa, "hemorrhagic ring" on border of glandular stomach with muscular stomach, edematous glandular envelope of trachea with hyperemia and point hemorrhages, accumulation of mucus with blood in trachea and large fibrinous- necrotic formations in intestine. Invention can be used for control of immunogenic activity of vaccines and in scientific and industrial laboratories in development of vaccines against Newcastle disease. EFFECT: valuable properties of strain. 2 tbl

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RU 2 192 278 C2

Authors

Lagutkin N.A.

Smirnov V.N.

Juzhuk T.Eh.

Lunitsin A.V.

Malogolovkina N.V.

Bobrovskaja N.K.

Balyshev V.M.

Dates

2002-11-10—Published

2000-11-28—Filed

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