FIELD: biotechnology, microbiological industry. SUBSTANCE: invention relates to production of antibiotics. Filtrate of cultural liquid of producer Fusidium coccineum is extracted with organic solvent and obtained reextract is treated with 25% sulfuric acid solution. Precipitate is crystallized by addition of methanol and purified fusidic acid is recrystallized with methanol aqueous solution with its concentration in solution 25%, not above. Fusidic acid is obtained as small-crystalline substance of crystal size 20 mcm, not above, as white powder containing impurities in the amount less 2%. EFFECT: high quality of fusidic acid.
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Authors
Dates
2002-11-10—Published
2000-09-05—Filed