VACCINE FOR ANTITUMOR IMMUNITY STIMULATION Russian patent published in 2002 - IPC

Abstract RU 2192884 C2

FIELD: medicine, oncology. SUBSTANCE: invention relates to vaccine used for stimulation of antitumor immunity. Invention involves vaccine composed of xenogenic tumor cells (murine carcinoma and melanoma cells) and xenogenic nontumor cells (porcine testicle cells) that are able to stimulate human antitumor immune responses efficiently. After penetration in body xenogenic cells are subjected for acute rejection mediated by natural antibodies and this process is accompanying with active implication of professional antigen-presenting (dendritic and macrophagial) cells in antitumor immune processes. EFFECT: enhanced antitumor immunity, valuable medicinal properties. 2 cl, 1 dwg, 1 tbl

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RU 2 192 884 C2

Authors

Seledtsov V.I.

Samarin D.M.

Seledtsova G.V.

Senjukov V.V.

Strunkin D.N.

Kozlov V.A.

Dates

2002-11-20Published

2000-11-09Filed