CRYSTALLINE MODIFICATIONS B AND C OF 1-(2,6-DIFLUORO-BENZYL)-1H-1,2,3-TRIAZOLE-4-CARBOXAMIDE AND PHARMACEUTICAL COMPOSITION Russian patent published in 2002 - IPC

Abstract RU 2194041 C2

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes novel modifications B and C of compound 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carbox-amide of the formula (I) and pharmaceutical composition showing anticonvulsant activity and comprising said crystalline modifications. Modifications exhibit higher rate of dissolving in water and gastric juice that is important in their using in therapeutic aims, for example, in acute attack of epilepsy. EFFECT: valuable medicinal properties of modifications. 14 cl, 1 tbl, 2 dwg, 3 ex

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RU 2 194 041 C2

Authors

Portmann Robert

Khofmajer Urs Kristof

Burkkhard Andreas

Sherrer Val'Ter

Shelagevich Martin

Dates

2002-12-10Published

1998-06-08Filed