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Application

2000111875/14, 2000-05-12

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Start date

2000-05-12

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Actual filing date

2000-05-12

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Published

2002-12-20

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Inventor

Pokrovskij M.V.Gladchenko M.P.Artjushkova E.B.Chernjatina M.A.Lebedev A.V.Tjupin R.N.Zubarev E.A.Brusnik M.S.

(73)

Holder

Pokrovskij Mikhail Vladimirovich

METHOD FOR EVALUATING CARDIOPROTECTIVE ACTION OF PHARMACOLOGICAL PRODUCTS AFTER MEASURING LEFT-VENTRICULAR PRESSURE AT MODELING ARTERIAL HYPERTENSION Russian patent published in 2002 - IPC

Abstract RU 2194436 C2

FIELD: medicine, experimental pharmacology and cardiology. SUBSTANCE: one should sound the cavity of left ventricle in narcotized rats. Left- ventricular pressure (LVP) is registered. Loading is carried out by 30-sec-long pinching an ascending aortic arch. As a criterion to evaluate cardioprotective action of studied pharmacological products one should use a LVP value on the 25th sec of aortic pinching expressed in percentage against the values on the 5th sec of aortic pinching. The method enables to reliably evaluate cardioprotective action of hypotensive products at experimental hypertension. EFFECT: higher efficiency of evaluation. 1 dwg

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RU 2 194 436 C2

Authors

Pokrovskij M.V.

Gladchenko M.P.

Artjushkova E.B.

Chernjatina M.A.

Lebedev A.V.

Tjupin R.N.

Zubarev E.A.

Brusnik M.S.

Dates

2002-12-20—Published

2000-05-12—Filed