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2 765 117

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IPC

A61K31/53(2006-01-01)

A61P9/10(2006-01-01)

A61P13/12(2006-01-01)

A61P25/00(2006-01-01)

A61P27/12(2006-01-01)

A61P3/10(2006-01-01)

C07D487/04(2006-01-01)

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Application

2019130147, 2019-09-24

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Start date

2019-09-24

(22)

Actual filing date

2019-09-24

(45)

Published

2022-01-25

(72)

Inventor

Babkova Valentina AndreevnaGovorova Yuliya AleksandrovnaGurova Nataliya AlekseevnaKotovskaya Svetlana KonstantinovnaLitvinov Roman AleksandrovichNaumenko Lyudmila VladimirovnaPetrov Vladimir IvanovichRusinov Vladimir LeonidovichSapozhnikova Irina MikhajlovnaSmirnov Aleksej VladimirovichSpasov Aleksandr AlekseevichShmidt Maksim Vyacheslavovich

(73)

Holder

Federalnoe Gosudarstvennoe Avtonomnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Federalnyj Universitet Imeni Pervogo Prezidenta Rossii B.N. Eltsina"Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

USE OF SODIUM SALT OF DIETHYL ESTER OF 4-OXO-1,4-DIHYDROPYRAZOLO[5,1-C]-1,2,4-TRIAZINE-3,8-DICARBOXYLIC ACID, MONOHYDRATE AS DRUG FOR TREATMENT AND PREVENTION OF LATE COMPLICATIONS OF DIABETES MELLITUS Russian patent published in 2022 - IPC A61K31/53 A61P9/10 A61P13/12 A61P25/00 A61P27/12 A61P3/10 C07D487/04

Abstract RU 2765117 C2

FIELD: medicine.

SUBSTANCE: invention relates to the use of sodium salt of diethyl ester of 4-oxo-1,4-dihydropyrazolo[5,1-c]-1,2,4-triazine-3,8-dicarboxylic acid, monohydrate of the formula I as a drug for the treatment and prevention of long-term consequences of diabetes mellitus. Sodium salt of diethyl ester of 4-oxo-1,4-dihydropyrazolo[5,1-c]-1,2,4-triazine-3,8-dicarboxylic acid, monohydrate is an effective drug for the treatment and prevention of such diabetic complications as nephropathy, cardiomyopathy, neuropathy, encephalopathy, endothelial dysfunction and hemorheological disorders; it can be widely used in medicine in the field of therapy of late complications of diabetes mellitus.

EFFECT: obtaining a drug for the treatment of complications of diabetes mellitus.

1 cl, 13 dwg

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RU 2 765 117 C2

Authors

Babkova Valentina Andreevna

Govorova Yuliya Aleksandrovna

Gurova Nataliya Alekseevna

Kotovskaya Svetlana Konstantinovna

Litvinov Roman Aleksandrovich

Naumenko Lyudmila Vladimirovna

Petrov Vladimir Ivanovich

Rusinov Vladimir Leonidovich

Sapozhnikova Irina Mikhajlovna

Smirnov Aleksej Vladimirovich

Spasov Aleksandr Alekseevich

Shmidt Maksim Vyacheslavovich

Dates

2022-01-25—Published

2019-09-24—Filed