APPLICATION OF THIAZOLIDINEDIONES FOR PREVENTION OR ONSET POSTPONEMENT OF INSULIN-INDEPENDENT DIABETES MELLITUS (NIDDM) Russian patent published in 2002 - IPC

FIELD: organic chemistry, medicine, endocrinology. SUBSTANCE: invention proposes a novel method of treatment of damaged tolerance to glucose in order to prevention or onset postponement of insulin-independent diabetes mellitus that involves administration of compounds of the general formula: or its tautomeric form, and/or solvate where A₅ means substituted or unsubstituted aromatic hydrocarbon group; A₆ means benzene ring having up to 5 substitutes; X₆ means O, S or NR₃₂ where R₃₂ means hydrogen atom, alkyl, acyl, aralkyl where aryl moiety can be substituted or unsubstituted, or substituted or unsubstituted aryl group; Y₂ means O or S; R₃₁ means alkyl, aralkyl or aryl; n = a whole number in the range form 2 to 6. EFFECT: expanded assortment of agents of claimed designation, valuable medicinal properties of compounds. 2 cl, 4 tbl, 1 ex