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2 135 494

(13)

(51)

IPC

(21) (22)

Application

96122851/04, 1996-11-29

(22)

Actual filing date

1996-11-29

(45)

Published

1999-08-27

(72)

Inventor

Takakhide NisiKoki IsibasiKatsujosi NakadzimaTetsuja FukazavaKhitosi KurataTakesi JamagutiKazukhiro Ito

(73)

Holder

Sankio Kompani Limited

HETEROCYCLIC COMPOUNDS AND COMPOSITION ON SAID SHOWING ANTAGONISTIC EFFECT WITH RESPECT TO TACHYKININ RECEPTORS Russian patent published in 1999 - IPC

Abstract RU 2135494 C1

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to compounds of the formula (I) and their quaternary ammonium derivatives of the formula (Ia) (value see in p. 1 of the claim) and composition based on said that show antagonistic effect with respect to neurokinin-1 and neurokinin-2 and can be used for treatment and prophylaxis of central nervous system diseases, respiratory sicknesses, allergy. EFFECT: enhanced effectiveness of treatment and prophylaxis. 95 cl, 10 tbl, 87 ex

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RU 2 135 494 C1

Authors

Takakhide Nisi

Koki Isibasi

Katsujosi Nakadzima

Tetsuja Fukazava

Khitosi Kurata

Takesi Jamaguti

Kazukhiro Ito

Dates

1999-08-27—Published

1996-11-29—Filed