METHOD FOR APPLYING GENETIC THERAPY OF VASCULAR DISEASES BY MEANS OF ACTIVE SUBSTANCE SPECIFIC TO CELL AND DEPENDANT ON CELLULAR CYCLE Russian patent published in 2003 - IPC

Abstract RU 2197992 C2

FIELD: medicine. SUBSTANCE: method involves applying DNA structure which essential element is activating sequence, proportion modulus and active substance gene. The activating sequence is excited in cell- specific way in smooth muscle cells, activated endothelium cells, activated macrophages or activated lymphocytes. This activation process is cell cycle-specifically controlled by promotion modulus. The active substance is a smooth muscle cells growth inhibitor and/or blood coagulation inhibitor. The described DNA- sequence is inserted into virus or non-virus vector completed with a ligand agent possessing affinity to target cell. EFFECT: enhanced effectiveness of treatment. 34 cl, 11 dwg

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RU 2 197 992 C2

Authors

Sedlachek Khans-Kharal'D

Mjuller Rol'F

Dates

2003-02-10Published

1995-08-25Filed