FIELD: medicine. SUBSTANCE: method involves applying DNA structure which essential element is activating sequence, proportion modulus and active substance gene. The activating sequence is excited in cell- specific way in smooth muscle cells, activated endothelium cells, activated macrophages or activated lymphocytes. This activation process is cell cycle-specifically controlled by promotion modulus. The active substance is a smooth muscle cells growth inhibitor and/or blood coagulation inhibitor. The described DNA- sequence is inserted into virus or non-virus vector completed with a ligand agent possessing affinity to target cell. EFFECT: enhanced effectiveness of treatment. 34 cl, 11 dwg
Authors
Dates
2003-02-10—Published
1995-08-25—Filed