SOLID PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING Russian patent published in 2003 - IPC

Abstract RU 2200002 C1

FIELD: pharmaceutical industry, pharmacy. SUBSTANCE: invention relates to medicinal agents used for prophylaxis, relieve or treatment of pathological states by disruption of parasitic organisms by means of chemical effect on their physiology. Invention relates to the development of solid pharmaceutical composition containing erythromycin base as an active substance that is mixed with potato starch, low-molecular polyvinylpyrrolidone, Tween-80 and talk. Method of its preparing involves wetting granulation, drying, dry granulation and calcium stearate, dry starch and talk are used for powdering. Starch sizing is used as wetting agent. Invention provides preparing medicinal preparation of high quality that retains its effect before intestine tract and protects stomach mucosa. Also, solid pharmaceutical composition shows suitable form for application of film cover and oral intake by patients being from newborns to adults. EFFECT: improved method of preparing, valuable properties of composition. 14 cl

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RU 2 200 002 C1

Authors

Kaminskaja M.I.

Jakovlev G.Ju.

Dmitrieva I.M.

Zaripova Z.I.

Prokop'Eva L.D.

Larina R.A.

Kalnina M.M.

Budimirova V.S.

Predeina N.I.

Dates

2003-03-10Published

2001-07-30Filed