PHARMACEUTICAL SOLID COMPOSITION ELICITING ANTITUBERCULOSIS EFFECT AND METHOD FOR ITS PREPARING Russian patent published in 2003 - IPC

Abstract RU 2207846 C1

FIELD: medicine, phthisiology, pharmacy. SUBSTANCE: invention proposes the composition comprising ethambutol as an active compound and starch, calcium or magnesium stearate, lactose, gelatin and talc as accessory inert substances taken in the following ratio of components, wt.-%: ethambutol hydrochloride, 60-65; lactose, 20-30; starch, 4.0-40; gelatin, 2.0-5.0; magnesium or calcium stearate, 0.2-1.0; talc, 0.2-3.0. Method involves preparing raw, mixing indicated active compound with a filling agent, wetting, granulation, drying, powdering with a powdering mixture and tabletting. Lactose is used as a filling agent. Wetting is carried out using the combined wetting agent comprising 8-12% solution of starch sizing and 8-12% gelatin solution. The composition is made as a tablet. EFFECT: valuable medicinal properties of composition. 3 cl

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RU 2 207 846 C1

Authors

Petukhova N.V.

Dmitrieva I.M.

Predeina N.I.

Dates

2003-07-10Published

2002-04-04Filed