METHOD FOR LOCAL INTRODUCTION OF PREPARATIONS IN CASE OF HEPATIC TUMORS Russian patent published in 2003 - IPC

Abstract RU 2200479 C2

FIELD: medicine, oncology. SUBSTANCE: it is suggested to inject preparation into portal vein of hepatic lobe-target (lobe-tumor-carrier) at occlusion of both afferent and efferent lobar vessels for 5-15 min. Teraphthal is used as such a preparation and after occlusion is over one should additionally inject ascorbic acid into the branch of portal vein. Or photosens is used as such a preparation and 10-35 min after occlusion is over one should carry out laser irradiation of tumor. The method provides predominant accumulation of preparations in hepatic lobe-target, their poor penetration into systemic blood flow that enables to decrease the dosage of preparation and its total toxicity. EFFECT: higher efficiency. 2 cl, 1 dwg, 7 tbl

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RU 2 200 479 C2

Authors

Vorozhtsov G.N.

Gal'Perin Eh.I.

Goloshchapov R.S.

Grachev S.V.

Djuzheva T.G.

Kazachkina N.I.

Kalija O.L.

Luzhkov Ju.M.

Luk'Janets E.A.

Nakhamijaev V.R.

Dates

2003-03-20Published

2000-12-07Filed