METHOD OF PANTHOHEMATOGEN-BASE PREPARATIONS PREPARING Russian patent published in 2003 - IPC

Abstract RU 2201240 C1

FIELD: medicine, technology of medicinal agents, pharmacy. SUBSTANCE: method involves the following stages: powder-like, dried, non-defibrinated blood of Siberian stag, Manchurian wapiti or sika deer is subjected for microcapsulation by preparing the preliminary soaking 8-10% aqueous solution of the above-indicated powder at temperature 30-35 C followed by addition of accessory material to prepared solution. Then the prepared solution is applied on microgranules made of accessory material in granulator device with fluidized bed and with their simultaneous drying. Then accessory-base material envelope is applied on microgranules surface, dried at temperature 38-40 C up to humidity 2%, not less, and calcium stearate is added in granulator device before unloading. Sugar and/or lactose, and/or glucose, and/or fructose, and/or sorbitol are used as accessory material. Ascorbic acid can be used as supplement that is added to solution of accessory material used in envelope applying. Method ensures to prepare preparations showing the enhanced fitness time and no requiring special storage conditions. EFFECT: improved method of preparing. 5 cl

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RU 2 201 240 C1

Authors

Vasina T.S.

Kuznetsov I.V.

Sinadskaja I.A.

Sheremet S.P.

Dates

2003-03-27Published

2001-11-16Filed