FIELD: medicine. SUBSTANCE: remedy has polar lipid composition on nicotine basis taken as liquid crystals and their colloid dispersions and in their predecessors or secondary products transformable into liquid crystals or liquid crystal mixtures. The composition operates as matrix of controllable nicotine release useable for giving up smoking and/or substituting smoking. The like compositions of liquid crystals or their dispersions or their predecessors or secondary products containing nicotine and anti- irritants or local analgesic or any their combinations alleviate irritating nicotine action or mask its taste. Available application paths involve buccal introduction like chewing gum produced from liquid crystals, or their dispersions or their predecessors or secondary products or buccal adhesives, gels and covers with liquid crystals, or their dispersions, or their predecessors, or secondary products and aerosol usable in peroral applications with dispersions of liquid crystals and their dispersions or their predecessors or secondary products, nasal aerosol and gel with the said liquid crystals, or their dispersions, or their predecessors or secondary products, local applications as adhesives, gels and covers with the said liquid crystals, or their predecessors, or secondary products being used. EFFECT: avoided adverse side effects; bioavalability; easiness in operation. 34 cl, 6 dwg, 5 tbl
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Authors
Dates
2003-04-10—Published
1998-09-15—Filed