GLYCYRRHETIC ACID SAPONIN SHOWING ANTIULCER ACTIVITY Russian patent published in 2003 - IPC

Abstract RU 2203285 C2

FIELD: organic chemistry of natural compounds, medicine, gastroenterology. SUBSTANCE: invention relates to novel chemical compounds, in part, to glycyrrhetic acid saponin, i. e. 6',6''-di-α-D-galactopyranosylcarboxylate ofglycyrrheticacid3-O-[2'-O-(β-D-glucuronopyranosyl)-β-D-glucuronopyranoside)-methyl ester of the formula (IIb) where R is Me; R2 is H eliciting an antiulcer activity. Compound (IIb) is a low-toxic substance showing the expressed antiulcer activity that exceeds effect of the known antiulcer preparation carbenoxolone by 2-fold at oral administration in 2 times less dose. EFFECT: enhanced effectiveness of agent, valuable medicinal properties. 1 tbl

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RU 2 203 285 C2

Authors

Kondratenko R.M.

Mustafina S.R.

Baltina L.A.

Vasil'Eva N.G.

Ismagilova A.F.

Bazekin G.V.

Galin F.Z.

Tolstikov G.A.

Dates

2003-04-27Published

2001-03-30Filed