AGENT IN FORM OF 8-(METHOXYCARBONYL)-4b,8-DIMETHYL-3-(2-METHYLPROPANOYL)-TETRADECAHYDROPHENANTHRENE-1,2,10a-TRICARBOXYLIC ACID AND PREPARATION METHOD THEREOF Russian patent published in 2011 - IPC C07C53/00 

Abstract RU 2426720 C1

FIELD: chemistry.

SUBSTANCE: invention relates to the chemical and pharmaceutical industry and specifically to an agent which is 8-(methoxycarbonyl)-4b,8-dimethyl-3-(2-methylpropanoyl)-tetradecahydrophenanthrene-1,2,10a-tricarboxylic acid of formula (I): , having low toxicity and marked anti-inflammatory and anti-ulcer activity. Described also is a method of producing 8-(methoxycarbonyl)-4b,8-dimethyl-3-(2-methylpropanoyl)-tetradecahydrophenanthrene-1,2,10a-tricarboxylic acid involving reaction of methyl ether of maleopimaric acid with ozone in methylene chloride medium at temperature 0°C with output of 89% after re-crystallisation.

EFFECT: improved properties of compounds.

2 cl, 2 ex, 2 tbl

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RU 2 426 720 C1

Authors

Kazakova Oksana Borisovna

Kukovinets Ol'Ga Sergeevna

Junusov Marat Sabirovich

Salimova Elena Viktorovna

Kazakov Dmitrij Valer'Evich

Chudov Ivan Vladimirovich

Ismagilova Asija Fakhretdinovna

Dates

2011-08-20Published

2009-11-30Filed