FIELD: medicine, endocrinology, pharmacy. SUBSTANCE: invention relates to the development of pharmaceutical composition eliciting antidiabetic effect based on derivative of oxovanadium (IV). Composition comprises bis-(L-malato)-oxovanadium (IV) and pharmaceutically acceptable vehicles. Invention provides the improvement of method of synthesis of bis- (L-malato)-oxovanadium (IV) also. EFFECT: valuable medicinal properties of composition, improved method of synthesis, expanded assortment of antidiabetic agents. 4 cl, 1 dwg, 6 tbl, 2 ex
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