SUBSTITUTED BIS-INDOLIMALEIMIDES DESIGNATED FOR INHIBITION OF CELL PROLIFERATION Russian patent published in 2003 - IPC

FIELD: organic chemistry, biology, pharmacy. SUBSTANCE: invention elates to novel substituted of bis-indolimaleimide of the formula (I) and their pharmaceutically acceptable salts also where R¹ means hydrogen atom; R² means methyl; or R¹ means methyl and R² means hydrogen atom; or R¹ mean hydroxymethyl and R² means methyl. Invention relates also to pharmaceutical composition eliciting an antiproliferative activity and comprising compound of the formula (I) and pharmaceutically acceptable carrier. Invention provides preparing the novel compound designated for inhibition of cells proliferation. EFFECT: valuable biological and medicinal properties of compounds. 5 cl, 8 tbl