FIELD: biotechnology, molecular biology, medicine, pharmacy. SUBSTANCE: invention relates to molecule of cellular surface of mammal. Transmembrane polypeptide takes part in regulation of activation of lymphocytes and it is produced by transformants comprising the expression vector where DNA encoding polypeptide is inserted. Also, antibody is constructed that is able to bind with polypeptide specifically and it is produced by hybridoma. Polypeptide is a component of pharmaceutical composition that is used for treatment or prophylaxis of disease caused by activation of lymphocytes. EFFECT: valuable biological and medicinal properties of polypeptide and antibody. 29 cl, 39 dwg, 19 ex
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Year |
Author |
Number |
| NON-HUMAN ANIMALS HAVING HUMANIZED LYMPHOCYTE-ACTIVATION GENE 3 |
2016 |
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|
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1998 |
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- Ostermann Ehlinborg
|
RU2238976C2 |
| ISOLATED POLYPEPTIDE POSSESSING ANTIVIRAL ACTIVITY (VARIANTS), POLYNUCLEOTIDE ENCODING ITS (VARIANTS), EXPRESSING VECTOR, RECOMBINANT CELL-HOST, METHOD FOR PREPARING POLYPEPTIDE, ANTIBODY SPECIFIC TO POLYPEPTIDE AND POLYPEPTIDE-CONTAINING PHARMACEUTICAL COMPOSITION |
2002 |
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RU2321594C2 |
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2002 |
|
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2013 |
- Tan Filip Khuat
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| POLYNUCLEOTIDE SEQUENCE ENCODING PROTOCADGERINE PC3, PC4, PC5 (VARIANTS), PROTOCADGERINE POLYPEPTIDE PC3, PC4, PC5 (VARIANTS) |
1995 |
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RU2197525C2 |
| HUMANIZED MONOCLONAL ANTIBODY RAISED AGAINST AILIM, CO-STIMULATING MOLECULE FOR SIGNAL TRANSFER AND ITS PHARMACEUTICAL APPLYING |
2001 |
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RU2262511C2 |
| MONOCLONAL ANTIBODIES AND METHODS OF USING THEM |
2017 |
- Britanova Olga Vladimirovna
- Izraelson Mark Aleksandrovich
- Lukyanov Sergej Anatolevich
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RU2694412C2 |
| IMMUNOSUPPRESSIVE POLYPEPTIDES AND NUCLEIC ACIDS |
2008 |
- Karrer Ehrik E.
- Pejdkhungat Madan M.
- Bejs Stiven Kh.
- Nejbors Margaret
- Punnonen Jukha
- Chepin Stiven Dzh.
- Visvanatkhan Sridkhar
- Larsen Brent R.
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RU2506275C2 |
| POLYPEPTIDE-LIGAND FLT3 (VARIANTS), POLYNUCLEOTIDE (VARIANTS), EXPRESSING VECTOR (VARIANTS), STRAIN OF CELL CHO (VARIANTS), METHOD FOR PRODUCING POLYPEPTIDE-LIGAND FLT3 (VARIANTS), PHARMACEUTICAL COMPOSITION (VARIANTS) |
1994 |
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