FIELD: medicine, cardiology, clinical medicine. SUBSTANCE: method involves additional prescription of polyene in the dose 3.6 g per 24 h for 2 intakes: in morning and evening for 28-30 days to patients with ischemia heart disease dosing with nitro-preparations, inhibitors of angiotensin - transforming ferments, β-antagonists and aspirin. Invention can be used for prophylaxis and recovery of cardiac rhythm in patients with ischemic heart disease. Method provides normalization of cardiac rhythm due to recovery of indices of rhythm variability and later potential values of ventricles of heart. EFFECT: enhanced effectiveness of prophylaxis and recovery. 8 tbl
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