FIELD: organic chemistry, biochemistry, medicine, pharmacy. SUBSTANCE: invention relates to new effectors of dipeptidylpeptidase IV, namely to dipeptide mimetics of the formula (I) given in the invention description and comprising of amino acid and thiazolidine or pyrrolidine group: L-alloisoleucylthiazolidine, L-alloisoleucylpyrrolidine and their salts, to salts of L-threo- isoleucylthiazolidine and L-threo-isoleucylpyrrolidine, pharmaceutical composition eliciting ability to reduce blood sugar level and containing at least one above indicated compounds of the formula (I). EFFECT: valuable medicinal properties of effectors. 20 cl, 4 dwg, 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| EFFECTORS OF DIPEPTIDYL PEPTIDASE IV | 1999 |
|
RU2309161C2 |
| NEW DIPEPTIDYL PEPTIDASE IV INHIBITORS AND USES THEREOF AS HYPOTENSIVE AGENT | 2002 |
|
RU2305553C2 |
| COMPOUNDS OF UNSTABLE INHIBITORS OF DIPEPTIDYLPEPTIDASE IV | 1999 |
|
RU2226195C2 |
| NOVEL INHIBITORS OF DIPEPTIDYL PEPTIDASE IV AND THEIR USING AS ANTICANCER AGENTS | 2002 |
|
RU2299066C2 |
| PRODRUGS OF DIPEPTIDYLPEPTIDASE IV INHIBITORS | 1999 |
|
RU2226533C2 |
| APPLICATION OF DPP-IV INHIBITOR FOR REDUCTION OF GLYCEMIA ACUTE EXACERBATION | 2006 |
|
RU2440143C2 |
| METHOD FOR IMPROVING SIGNAL TRANSFER IN ISLETS OF LANGERHANS IN DIABETES MELLITUS AND IN ITS PROPHYLAXIS | 2001 |
|
RU2261096C2 |
| INHIBITORS OF DIPEPTIDYL PEPTIDASE IV | 2001 |
|
RU2280035C2 |
| PHARMACEUTICAL COMPOSITIONS | 2010 |
|
RU2532330C2 |
| COMBINATION OF DIPEPTIDILPEPTIDASE IV (DPP IV) INHIBITOR AND CARDIOVASCULAR SUBSTANCE | 2003 |
|
RU2336876C2 |
