FIELD: organic chemistry, chemical technology.
SUBSTANCE: invention relates to a method for preparing hydroxymethylthiobutyric acid esters that involves the following stages: (a) the first step of interaction of 2-hydroxy-4-methylthiobutyronitrile with sulfuric acid for preparing 2-hydroxy-4-methylthiobutyramide; (b) the second step of interaction of 2-hydroxy-4-methylbutyramide with alcohol for preparing 2-hydroxy-4-methylthiobutyric acid ester. Both stages are carried out in a single reaction medium. Method provides preparing esters from nitriles avoiding the preparing acid by using the same reaction medium for stages of hydrolysis and esterification.
EFFECT: improved preparing method.
13 cl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PREPARING FREE ALPHA-HYDROXY ACIDS FROM AMMONIUM SLATS THEREOF (VARIANTS) | 1997 |
|
RU2165407C2 |
| METHOD FOR CATALYTIC CONVERSION OF 2-HYDROXY-4-METHYLTHIOBUTANE NITRILE (HMTBN) TO 2-HYDROXY-4-METHYLTHIOBUTANE AMIDE (HMTBA) | 2008 |
|
RU2479574C2 |
| METHOD OF OBTAINING AMMONIUM SALT OF 2-HYDROXY-4-METHYLTHIOBUTYRIC ACID | 2004 |
|
RU2355678C2 |
| METHOD OF PRODUCING FREE ACIDS FROM SALTS THEREOF | 2010 |
|
RU2533413C2 |
| STORAGE-STABLE NITRILE OF 2-HYDROXY-4-(METHYLTHIO) BUTYRIC ACID | 2012 |
|
RU2597264C2 |
| METHOD FOR PRODUCING OLEFIN BY CATALYTIC CONVERSION OF AT LEAST ONE ALCOHOL | 2014 |
|
RU2660132C2 |
| METHOD OF SYNTHESIS OF 2-HYDROXY-4-METHYLTHIO-BUTANOIC ACID | 1998 |
|
RU2184111C2 |
| METHOD FOR PRODUCING 2-HYDROXY-4-(METHYLTHIO)BUTANENITRILE FROM 3-(METHYLTHIO)PROPANAL AND HYDROGEN CYANIDE | 2012 |
|
RU2604534C2 |
| METHOD OF PRODUCING METHIONINE | 2016 |
|
RU2708258C2 |
| METHOD FOR PRODUCING ACROLEIN FROM GLYCERINE | 2013 |
|
RU2644767C2 |
