METHOD FOR PREPARING VITAMIN COMPLEX AS DRAGEE Russian patent published in 2004 - IPC

FIELD: medicine, pharmacology, pharmaceutical technology.

SUBSTANCE: method for preparing vitamin complex is based on water- and lipid-soluble vitamins, such as retinal acetate, thiamine chloride, riboflavin, pyridoxine hydrochloride, ascorbic acid, α-tocopherol acetate, nicotinamide, folic acid, calcium pantothenate, cyanocobalamin taken in the pharmacologically permitted amounts by multiple-stage pelleting granules. Kestose is used as saccharide powder and each layer of vitamin or vitamins mixture overfilled with kestose is wetted with kestose-containing pouring syrup with addition of starch molasses in the content of dry matters 66-68.5%. After by-layer knurling all vitamins dragee is calibrated to required size, dried, covered by kestose- and starch molasses-containing protecting layer with the content of dry matters 80.0-81.0%, knurled with kestose, covered by the second protecting layer with the content of dry matters 81.0-83.0% and then prepared dragee is covered by wax-lipid composite. In carrying out the by-layer knurling vitamins ergocalciferol is added to a lipid-containing layer additionally. Invention provides the development of the effective and completely assimilable safety preparation.

EFFECT: improved preparing method, improved and valuable properties of preparation.

2 cl, 2 ex