FIELD: medicine, endocrinology, pharmacy.
SUBSTANCE: antidiabetic pharmaceutical composition comprises 5-[[4-[3-methyl-4-oxo-3,4-dihydro-2-quinazolinyl]methoxy]phenylmethyl]-thiazolidine-2,4-dione or its pharmaceutically acceptable salt, lactose, microcrystalline cellulose and magnesium stearate and/or talk. Composition can be made as a table, powder or capsule. Method for preparing the composition involves preparing the mixture of indicated components and direct pressing the mixture. New pharmaceutical composition exhibits the improved stability, in particular, its solid medicinal formulations.
EFFECT: improved and valuable pharmaceutical properties of composition.
6 cl, 2 tbl, 9 ex
Title | Year | Author | Number |
---|---|---|---|
NOVEL DERIVATIVES OF AZOLIDINEDIONE, METHOD OF THEIR SYNTHESIS (VARIANTS), PHARMACEUTICAL COMPOSITIONS BASED ON THEREOF, METHOD OF PROPHYLAXIS OR TREATMENT, METHOD OF GLUCOSE LEVEL DECREASE AND INTERMEDIATE COMPOUND | 1997 |
|
RU2200161C2 |
AGENT FOR ENHANCING CORNEAL EPITHELIAL BARRIER FUNCTION | 2009 |
|
RU2484848C2 |
NEW COMBINATION OF 3-[(3-{[4-(4-MORPHOLINYLMETHYL)-1N-PYRROL-2-YL]METHYLENE}-2-OXO-2,3-DIHYDRO-1N-INDOL-5-YL)METHYL]-1,3-THIAZOLIDINE-2,4-DIONE AND TYROSINE KINASE INHIBITOR EGFR | 2016 |
|
RU2695362C2 |
NOVEL COMPOSITION | 2006 |
|
RU2483716C2 |
NEW COMPOSITION | 2006 |
|
RU2821230C2 |
METHOD FOR TREATING METABOLISM DISORDERS MAINLY DIABETES CASES AND DISEASES OR STATES RELATED TO DIABETES | 2000 |
|
RU2280447C2 |
PHARMACEUTICAL ANTI-DIABETIC COMPOSITION BASED ON SUBSTITUTED THIOPHENE CARBOXYLATE AND A METHOD FOR PRODUCTION THEREOF | 2018 |
|
RU2688235C1 |
COMBINATION CONTAINING A COMPOUND OF ANGIOTENSIN II-ANTAGONISTIC ACTIVITY | 1997 |
|
RU2188013C2 |
SOLID DOSAGE FORM OF ANTIDIABETIC DRUG BASED ON N-SUBSTITUTED DERIVATIVE AMRINONE - KINASE INHIBITOR OF GLUCOGEN SYNTHASE | 2016 |
|
RU2663913C1 |
APPLICATION OF HYPOGLYCEMIC AGENT FOR TREATING AFFECTED GLUCOSE METABOLISM | 2000 |
|
RU2264811C2 |
Authors
Dates
2004-08-10—Published
1999-11-29—Filed