FIELD: medicine; pharmaceutics.
SUBSTANCE: invention refers to medicine and pharmaceutical industry and concerns a pharmaceutical composition, which is a tablet, which contains as active ingredients: 1) 50 mg of vildagliptin and 500 mg of metformin, 2) 50 mg of vildagliptin and 850 mg of metformin, or 3) 50 mg of vildagliptin and 1000 mg of metformin or in each case pharmaceutically acceptable salts thereof, wherein the active ingredients correspond to 60 to 98% of the composition, and in which metformin is in the form of granules containing from 1 to 20 wt.% based on the weight of the dry pharmaceutically acceptable binding agent selected from cellulose and its derivatives. Also disclosed is a method of producing said composition.
EFFECT: implementation of the assignment.
37 cl, 8 tbl, 7 ex
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