FIELD: medicine, pharmaceutical industry, pharmacy.
SUBSTANCE: invention relates to manufacturing medicinal formulations, namely, to medicinal preparation interferon. Preparation is made as sublingual tablets comprising human recombinant alpha-2-interferon prepared by methods of genetic engineering as an active substance that is taken in the definite dose and accessory substances also. In making tablets an active substance is mixed with polyvinylpyrrolidone and added to dry mixture of lactose or sucrose and starch followed by addition of polyethylene glycol, calcium stearate and tableting. Invention provides the development of new medicinal formulation of interferon.
EFFECT: improved preparing method, improved and valuable medicinal and pharmaceutical properties.
3 cl, 1 tbl, 3 ex
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Authors
Dates
2004-08-27—Published
2003-05-07—Filed