ANTIVIRAL AND ANTIMICROBIAL COMPOSITION Russian patent published in 2012 - IPC A61K38/21 A61K9/14 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical industry and medicine. A composition represents a powder containing a substance comprising recombinant human interferon-α and target additives able to form a stable foam structure, specified in: polyethylene glycol, albumin, gelatine, pectin, casein, caseinate, casein hydrolysate, hydroxypropyl cellulose, polyglucin, dextrin, tragacanth, aerosil, mannitol or their mixtures; it is characterised by porous structure and fragility, has a relative disintegration shrinkage at least 10 %, equivalent pore diameter 10-110 mcm at particle size no more than 100 mcm and a resting angle less than 50° in the following proportions in 1.0 g of the composition: recombinant human interferon-α - 10000-3000000 IU, target additives - the rest. The invention provides the isotropic filling of the 100% preset volume of drug containers that exceeds the effect of a similar composition by 5% and more showing no combination of the structural and mechanical properties of the declared composition.

EFFECT: maximum isotropic filling of the preset volume of the drug containers ensures precise dosages of recombinant human interferon-α.

3 cl, 4 ex