FIELD: organic chemistry, medicine.
SUBSTANCE: invention relates to a disinfecting agent among class of quaternary ammonium compounds. Agent represents a mixture of alkylcetylpyridinium chlorides prepared by esterification of monochloroacetic acid with synthetic saturated alcohol of (C12-C14)-fraction, (C12-C18)-fraction or (C16-C18)-fraction in their mole ratio = 1.1:1 in organic solvent medium at temperature 75-85oC followed by interaction of prepared alkylchloroacetate with pyridine in the mole ratio = 1:(1.0-1.1)for 6-9 h at temperature 80-90oC and recrystallization of the end product from organic solvent. Melting point of the end product is 98-103oC, content of chloride ions is 8.5-9.9%. This disinfecting agent is used in medicine, agriculture and in homes and elicits disinfecting effect with respect to vegetative, capsule and spore-forming forms of microorganisms. Agent elicits bactericidal effect with respect to test-cultures of E. coli, S. aureus, Ps. aeruginosa in the concentration ≥ 0.5 mas.% at exposition for 60 min and bacteriostatic effect with respect to Bac. subtilis in the concentration 5 mas.% and exposition for 120 min. Invention provides preparing the novel disinfecting agent eliciting improved properties.
EFFECT: expanded assortment of native disinfecting agents.
2 tbl, 6 ex
Title | Year | Author | Number |
---|---|---|---|
DISINFECTING AGENT | 2004 |
|
RU2279275C2 |
N,N-DIMETHYL-N-ALKYL-N-[ALKOXYPOLY(ETHYLENEOXY)- CARBONYLMETHYL]AMMONIUM CHLORIDES ELICITING FUNGISTATIC AND BACTERICIDAL ACTIVITY AND ADDITION AGENT PROPERTY REGULATING VASOELASTIC PROPERTY OF ASSOCIATED MULTICOMPONENT PETROLEUM SYSTEM AND METHOD FOR THEIR PREPARING | 2002 |
|
RU2221776C2 |
ANTI-INFECTIVE AGENT | 2004 |
|
RU2275193C2 |
TRIS-[(AMMONIO)METHYLCARBONYLOXYPOLY-(2-METHYLETHYLENOXY)]PROPANE TRICHLORIDES POSSESSING PROPERTY OF EMULSIFIER OF AQUEOUS-BITUMEN EMULSIONS AND METHOD FOR THEIR PREPARING | 2005 |
|
RU2294337C1 |
METHOD FOR PRODUCTION OF POLYALKYLMETHACRYLATE ADDITIVE (VARIANTS) AND POLYALKYLMETHACRYLATE ADDITIVE (VARIANTS) | 2004 |
|
RU2280652C1 |
METHOD FOR PRODUCING MONOCHLORALKANES | 1992 |
|
RU2009117C1 |
N-[ALKYLPHENOXYPOLY(ETHYLENEOXY)CARBONYLMETHYL]-MORPHOLINIUM CHLORIDES POSSESSING PROPERTY OF INHIBITORS OF ASPHALT-RESIN-PARAFFIN DEPOSITS, METHOD FOR THEIR PREPARING | 2007 |
|
RU2322435C1 |
{[1-(AMMONIO)-3,5,7-TRIAZAADAMANTYL]-METHYLCARBONYLOXYPOLY-(ALKYLENEOXY)}PROPANE CHLORIDE POSSESSING BACTERICIDAL AND FUNGICIDE ACTIVITY AND METHOD FOR THEIR PREPARING | 2005 |
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RU2288920C1 |
DISINFECTING AGENT | 2005 |
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RU2297248C1 |
CONDITIONING SHAMPOO COMPOSITIONS | 2007 |
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RU2466711C2 |
Authors
Dates
2004-10-20—Published
2002-12-03—Filed