FIELD: biotechnology, pharmaceutical industry, medicine, pharmacy.
SUBSTANCE: invention is designated for producing stable an aqueous solution of albumin-free genetic engineering interferon-α2 for injection that is necessary for treatment of different viral and oncological diseases. Human interferon α2 for injection comprises buffer for maintaining pH value of solution in the range 4.5-7.0, non-ionic detergent, preserving agent eliciting an antibacterial activity, an agent providing isotonic property of solution, water for injection and, additionally, it comprises oxidized glutathione and/or citric acid for prevention of interferon activity loss. Method provides preparing interferon-α2 solution for injection that is stable under standard storage conditions (5o C) and in storage under conditions of elevated temperature (25o C, 35o C).
EFFECT: improved and valuable properties of interferon solution.
3 cl, 1 tbl, 9 ex
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