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2 564 951

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IPC

A61K9/08(2006-01-01)

A61K38/21(2006-01-01)

A61K47/30(2006-01-01)

A61K33/14(2006-01-01)

(21) (22)

Application

2014135240/15, 2014-08-28

(24)

Start date

2014-08-28

(22)

Actual filing date

2014-08-28

(45)

Published

2015-10-10

(72)

Inventor

Sharypova Mar'Jana Grigor'EvnaNaumova Nina Vasil'EvnaSmolina Margarita PetrovnaVojtenko Aleksandr Vasil'EvichTargonskaja Oksana ViktorovnaTargonskij Sergej Nikolaevich

(73)

Holder

Zakrytoe Aktsionernoe Obshchestvo

COMPOSITION OF AQUEOUS SOLUTION OF RECOMBINANT HUMAN INTERFERON ALPHA-2 FOR RECTAL ADMINISTRATION Russian patent published in 2015 - IPC A61K9/08 A61K38/21 A61K47/30 A61K33/14

Abstract RU 2564951 C1

FIELD: medicine.

SUBSTANCE: composition of an aqueous solution of recombinant human interferon alpha-2 contains: recombinant human interferon alpha-2 25.0-200.0 thousand International Units, sodium alginate 10.0-100.0 mg, antioxidant oxidised glutathione 0.006-0.1 mg, the antimicrobial preserving agent Nipagin 0.2-1.8 mg, the stabilising agent Polysorbate 80 (Tween 80) 0.01-1.0 mg, sodium chloride 5.8-7.5 mg, a buffer compound for balancing pH 4.5-7.0 10.0-25.0 mM, water - the rest up to 1 ml.

EFFECT: using the given composition enables creating the aqueous solution of extended release recombinant human interferon alpha-2 for rectal administration.

3 cl, 4 tbl, 2 dwg

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RU 2 564 951 C1

Authors

Sharypova Mar'Jana Grigor'Evna

Naumova Nina Vasil'Evna

Smolina Margarita Petrovna

Vojtenko Aleksandr Vasil'Evich

Targonskaja Oksana Viktorovna

Targonskij Sergej Nikolaevich

Dates

2015-10-10—Published

2014-08-28—Filed