METHOD FOR TREATING MALIGNANT TUMORS WITH INTRATISSULAR RADIATION THERAPY Russian patent published in 2005 - IPC

FIELD: medicine.

SUBSTANCE: method involves making tumor infiltration with radioactive solution. Injection needle is introduced as deep as one half of tumor thickness. The first radioactive solution portion is introduced with automatic injector device according to given program under radiometric control. Then, the following portions are introduced. Specific activity ratio in preceding and following portion is equal to 7:1, volume ratio in preceding and following portion is equal to 1:3 and activity ratio in preceding and following portion is equal to 2:1. Radioactive solution volumes in preceding (V₁) and following (V₂) portion is determined from relations V₀=V_tumor/3; V₁= V₀/4 and V₂=3 V₁, where V₀ is the total volume planned for applying intratissular radiation therapy, V_tumor is the tumor volume. Radioactive solution activity preceding (A₁) and following (A₂) portion is determined from relations A₁= 0.66A₀ and V₂=0.33A₀, where A₀ is the total activity planned for applying intratissular radiation therapy. Radioactive solution feeding rate is set not greater than 1.0 cm³/min.

EFFECT: wider effective action zone; reduced risk of traumatic complications; wider range of indications to applying the therapy.

4 cl, 1 dwg, 1 tbl