METHOD FOR PREPARING 2-KETO-L-GULONIC ACID Russian patent published in 2005 - IPC

FIELD: organic chemistry, chemical technology.

SUBSTANCE: invention relates to the improved method for preparing 2-keto-L-gulonic acid. This compound is an intermediate substance in synthesis of vitamin C. Method involves oxidation of L-sorbose in the presence of platinum-containing polymeric catalyst applied on Al₂O₃ in medium with the equimolar content of NaHCO₃ under atmosphere pressure, at the rate stirring 870-1 000 rev/min and bubbling pure oxygen as an oxidizing agent. Reaction is carried out in medium water : ethyl alcohol 7-10 vol. %, in the concentration of L-sorbose 0.29-0.6 mole/l, on spherical microparticles of catalyst in the amount 20-40 g/l with ultra-thin layer of polydiallyldimethylammonium chloride as cationic polyelectrolyte with platinum nanoparticles formed on it. The content of platinum in catalyst is 1-2%. The feeding rate of oxidizing agent is 400-450 ml/min. The end product is obtained with high yield 97-99%.

EFFECT: improved preparing method, enhanced yield of product.

7 cl, 1 tbl, 1 sch, 7 ex