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IPC

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Application

2003108419/15, 2003-03-27

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Start date

2003-03-27

(22)

Actual filing date

2003-03-27

(45)

Published

2005-03-10

(72)

Inventor

Osipova I.G.Chumaeva T.V.Vasil'Eva E.A.Dalin M.V.Evlashkina V.F.Zolotareva O.V.

(73)

Holder

Osipova Irina Grigor'EvnaChumaeva Tat'Jana VladimirovnaVasil'Eva Elena AleksandrovnaDalin Mikhail ViktorovichEvlashkina Vera Frantsevna

METHOD FOR ESTIMATION OF SPECIFIC ACTIVITY OF DIFFERENT MEDICINAL FORMULATION PROBIOTICS AND INDUSTRIAL STRAINS BY LEVEL OF THEIR ADHESIVE ACTIVITY Russian patent published in 2005 - IPC

Abstract RU 2247570 C2

FIELD: medicinal microbiology, biotechnology.

SUBSTANCE: invention relates to a method for assay of specific activity of probiotics and industrial strains that involves determination of the amount of viable microorganisms. The level of viable microorganisms are determined by their adhesive capacity activity with respect to human erythrocytes. Method provides reducing time for assay of the specific activity up to 2-3 h and with using available reagents. Invention can be used as the express-method for estimation of the level of the specific activity (amount of live microorganisms in the preparation dose) of probiotics of different medicinal formulations (lyophilized biomass, tablet and suppository), and industrial strains by the level of their adhesive activity.

EFFECT: improved method for estimation.

3 cl, 5 tbl, 8 ex

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RU 2 247 570 C2

Authors

Osipova I.G.

Chumaeva T.V.

Vasil'Eva E.A.

Dalin M.V.

Evlashkina V.F.

Zolotareva O.V.

Dates

2005-03-10—Published

2003-03-27—Filed