METHOD OF PREPARING TRANS-3,4-DIALKYLCYCLOPENTAN-1-OLS Russian patent published in 2005 - IPC

FIELD: organic synthesis.

SUBSTANCE: invention relates to a novel method fir preparing trans-3,4-dialkylcyclopentan-1-ols having general formula 1:

(1),

where R represents n-butyl, n-hexyl, or n-octyl, which can find use in fine organic synthesis, production of lacquer materials, high-efficiency antiscoring and antiwear additives for lubricating oils, and biologically active substances. Method is characterized by that α-olefins having general formula RCH=CH₂ (R as above) are brought into reaction with ethylaluminum dichloride EtAlCl₂ and magnesium at molar ratio 10:(5-7):(5-7), respectively, in presence of zirconacene dichloride Cp₂ZrCl₂ as catalyst at molar ratio of the latter to α-olefin 0.03-0.07 under argon atmosphere, at room temperature and atmospheric pressure in tetrahydrofuran medium, after which nickel chloride phosphine complex [NiCl₂·2Ph₃P] is added at molar ratio to α-olefin 0.08-0.12 and methyl formate in amount trice as great as that of EtAlCl₂. Yield of desired product is 54-72%.

EFFECT: optimized synthesis conditions.

1 tbl, 13 ex