PHARMACOKINETIC AND PHARMACODYNAMIC MODELLING IN ADMINISTRATION OF ERYTHROPOIETIN Russian patent published in 2005 - IPC

Abstract RU 2248215 C2

FIELD: medicine, pharmacology.

SUBSTANCE: invention relates to method for assay of optimized regimens in dosing erythropoietin (EOR). Invention proposes a system for election of one or some regimens in dosing by using pharmacokinetic/pharmacodynamic (PK/PD) as a model for assay of PK/PD pattern regimens. Then method involves selection of such regimen that provides the serum concentration of EOR exceeding its before administration for 5-30 days between administrations of EOR. Invention provides optimal applying EOR for correction of blood indices changes and treatment of diseases associated with them.

EFFECT: improved and valuable modeling method.

50 cl, 81 dwg, 2 tbl, 8 ex

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RU 2 248 215 C2

Authors

Cheung Ving

Gibson Dehvid

Kout Kristin

Verkammen Ehls

Dates

2005-03-20Published

2000-05-10Filed