HEPARIN CONCENTRATION DETERMINATION METHOD Russian patent published in 2005 - IPC

Abstract RU 2249819 C2

FIELD: analytical methods in medicine.

SUBSTANCE: invention concerns hematological procedures and, in particular, can be used in heparin treatment practice. Method of invention is based on measuring rate of thrombin-mediated hydrolysis of a chromogenic substrate, thrombin having activity 0.5-0.6 unit/ml and chromogenic substrate being z-Ala0Ala-Arg-pNA·HBr.

EFFECT: extended assortment of home reagents, simplified preparation procedure, and increased sensitivity of method.

1 dwg, 3 tbl, 2 ex

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RU 2 249 819 C2

Authors

Mamaev A.N.

Momot A.P.

Makarov V.A.

Vojushina T.L.

Shakhmatov I.I.

Dates

2005-04-10Published

2003-05-22Filed