FIELD: medicine. SUBSTANCE: invention relates to methods of laboratory diagnosis. Method involves plasma blood research by addition of chromogenic peptide substrates to plasma sample followed by assay of degree of their hydrolysis. Method involves the use of substance of the chemical structure: z-Ala-Ala-Arg-pNa . R where R is an acid as a chromogenic substrate. EFFECT: simplified method of antithrombin III activity assay.
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