FIELD: virology, veterinary.
SUBSTANCE: invention relates to thermosensitive strain of horse abortion herpes virus ENV-1, pharmaceutical composition, vaccine and method for animal immunization based on the same. Strain replication is limited by upper respiratory tract and doesn't cause of viremia. Furthermore strain has insufficient growth at temperature of wild-type virus normal growth. Strain of present invention, as well as compositions and vaccines based on the same are useful in clinical and viral horse protection against ENV-1 infections, viral induced abortion and paresis.
EFFECT: new pharmaceutical composition, vaccine and method for horse immunization.
4 cl, 10 tbl, 7 ex
Authors
Dates
2005-05-20—Published
2000-09-11—Filed