FIELD: pharmaceutical industry, medicine.
SUBSTANCE: invention relates to human insulin drug of durable action. Drug contains human insulin substance of high purity, protamine sulfate, zinc chloride, glycerol, m-cresol, phenol, sodium dihydrogenphosphate dihydrate or disodium hydrogenphosphate heptahydrate, sodium chloride, and water and has residual proteolysis activity not more than 0.005 adsorption units.
EFFECT: human insulin drug of durable action with increased physiological activity and physical and chemical storage stability.
4 ex, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| HUMAN INSULIN DRUG OF SHORT ACTION | 2003 |
|
RU2252752C2 |
| METHOD FOR PRODUCTION OF INSULIN DRUG OF DURABLE ACTION | 2002 |
|
RU2252782C2 |
| METHOD FOR PREPARING HUMAN INSULIN COMBINED PREPARATION | 2002 |
|
RU2261108C2 |
| METHOD FOR PREPARING PHARMACEUTICAL COMPOSITION SUSPENSION BASED ON SUBSTANCE OF HUMAN GENETIC ENGINEERING (RECOMBINANT) INSULIN | 2004 |
|
RU2281756C2 |
| CARBOHYDRATE-CONTAINING INSULIN PREPARATIONS | 1997 |
|
RU2204411C2 |
| METHOD OF PREPARING PHARMACEUTICAL COMPOSITION SUSPENSION BASED ON SUBSTANCE OF GENETIC ENGINEERING (RECOMBINANT) HUMAN INSULIN | 2001 |
|
RU2185152C1 |
| METHOD OF PREPARING PREPARATION "PENSULIN CC" OF INSULIN SUSPENSION FOR CARTRIDGE | 1999 |
|
RU2157698C1 |
| INSULIN PREPARATION CONTAINING NACL, PARENTERAL FINISHED FORM, METHOD FOR INCREASING CHEMICAL STABILITY OF INSULIN PREPARATION | 1997 |
|
RU2182015C2 |
| METHOD FOR PREPARING READY MEDICINAL FORMULATION OF INSULIN WITH SHORT EFFECT | 2002 |
|
RU2261107C2 |
| COMPLEX OF INSULIN ANALOG AND PROTAMINE, METHOD OF PREPARING, PHARMACEUTICAL COMPOSITION AND METHOD OF DIABETIC TREATMENT | 1995 |
|
RU2154494C2 |
