FIELD: medicine, endocrinology, hormones, pharmacy. SUBSTANCE: invention relates to different parenteral pharmaceutical compositions that have monomeric insulin analog, zinc, protamine and phenolic derivative. Compositions of analog provide prolonged effect. Invention describes also method of preparing the composition insulin analog-protamine. Invention involves also description of method of treatment of diabetics using the complex of insulin and protamine and pharmaceutical composition containing said. EFFECT: development of agents used for treatment of diabetics, prolonged effect of agent. 31 cl, 1 tbl, 13 ex, 3 dwg
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