FIELD: organic chemistry, medicine, oncology, pharmacy.
SUBSTANCE: invention relates to pharmaceutical composition comprising the known antibiotic eliciting an antitumor activity and derivative of hydroxamic acid of the formula (1) 
wherein the weight ratio of two active agents is (1:50)-(50:1), respectively. The composition reduces adverse effects and elicits the enhanced antitumor effect.
EFFECT: improved valuable medicinal properties of composition.
4 cl, 1 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PHARMACEUTICAL COMPOSITION ELICITING ANTITUMOR EFFECT WITH REDUCED ADVERSE EFFECTS AND CONTAINING ANTITUMOR AGENT AND DERIVATIVE OF HYDROXAMIC ACID | 1998 |
|
RU2214238C2 |
| PHARMACEUTICAL COMPOSITION POSSESSING ANTIPSYCHOTIC, ANTIDEPRESSANT AND ANTIEPILEPTIC ACTIVITY WITH REDUCED SIDE EFFECT | 2007 |
|
RU2440116C2 |
| SYNERGETIC PHARMACEUTICAL COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF DIABETES MELLITUS | 2002 |
|
RU2311907C2 |
| OVERWEIGHT OR OBESITY REDUCTION | 2007 |
|
RU2443417C2 |
| PHARMACEUTICAL COMPOSITIONS COMPRISING DERIVATIVES OF HYDROXAMIC ACID | 1996 |
|
RU2191005C2 |
| DERIVATIVES OF N-SUBSTITUTED INDOLE-3-GLYOXYLAMIDE AS ANTITUMOR MEDICINAL AGENT AND AGENT INHIBITING ANGIOGENESIS (VARIANTS) AND ANTITUMOR MEDICINAL AGENT (VARIANTS) | 2000 |
|
RU2282444C2 |
| PRODRUG FOR THERAPY OF TUMORS AND INFLAMMATORY DISEASES | 1997 |
|
RU2191021C2 |
| DERIVATIVES OF INDOLYL-3-GLYOXYLIC ACID - COMPOUNDS ELICITING ANTITUMOR ACTIVITY, PHARMACEUTICAL COMPOSITION, ANTITUMOR AGENT (VARIANTS) | 1999 |
|
RU2262339C2 |
| COMBINATION CONTAINING IRON COMPLEX AND ANTINEOPLASTIC AGENT, AND USE THEREOF | 2007 |
|
RU2469721C2 |
| IBAT INHIBITOR FOR TREATING HEPATIC DISORDERS | 2011 |
|
RU2591188C2 |
